Phosphine, [(1S,4S)-1,4-dimethyl-1,4-butanediyl]bis[diphenyl- (9CI) - Names and Identifiers
Name | Phosphine, [(1S,4S)-1,4-dimethyl-1,4-butanediyl]bis[diphenyl- (9CI)
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Synonyms | (2S,5S)-Hexane-2,5-diylbis(diphenylphosphine) Phosphine, [(1S,4S)-1,4-dimethyl-1,4-butanediyl]bis[diphenyl- (9CI)
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CAS | 216019-41-9
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Phosphine, [(1S,4S)-1,4-dimethyl-1,4-butanediyl]bis[diphenyl- (9CI) - Physico-chemical Properties
Molecular Formula | C30H32P2
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Molar Mass | 454.52 |
Boling Point | 556.1±33.0 °C(Predicted) |
Phosphine, [(1S,4S)-1,4-dimethyl-1,4-butanediyl]bis[diphenyl- (9CI) - Introduction
Phosphine, [(1S,4S)-1,4-dimethyl-1, 4-butylyl] bis [diphenylyl- (9CI) is an organophosphorus compound with the chemical formula C34H38P2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
Phosphine, [(1S,4S)-1,4-dimethyl-1, 4-butylyl] bis[diphenyl- (9CI) is a colorless or light yellow solid, soluble in some organic solvents such as dichloromethane, ethanol and ether. It is a chiral compound with two enantiomers, namely (2S,5S) and (2R,5R). Its melting point and boiling point are between 120-125°C and 340-360°C, respectively.
Use:
Phosphine, [(1S,4S)-1,4-dimethyl-1, 4-butylyl] bis[diphenyl- (9CI) is often used as a ligand or catalyst precursor in organic synthesis. It can form stable complexes with transition metals and participate in various catalytic reactions, such as asymmetric hydrogenation, asymmetric hydroborane, etc. The compound is widely used in the field of drug synthesis, natural product synthesis and material chemistry.
Method:
Phosphine, [(1S,4S)-1,4-dimethyl-1, 4-butylyl] bis[diphenyl- (9CI) can be prepared by enantioselective phosphate esterification. A common synthetic method is the use of bromohexane and diphenylphosphine in the presence of chiral phosphonic acids. The reaction conditions and specific steps can be adjusted according to specific needs.
Safety Information:
Phosphine, [(1S,4S)-1,4-dimethyl-1, 4-butylyl] bis [diphenylyl- (9CI) under the conditions of correct use and storage, it is generally a relatively safe compound. However, because it is an organic compound and has a chiral structure, it should still comply with relevant operating regulations and safe operating procedures. Avoid contact with oxygen, strong oxidants and flammable substances, prevent them from moisture and avoid prolonged contact with skin and eyes. Appropriate personal protective equipment such as goggles, gloves and laboratory clothing should be worn during operation. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
Last Update:2024-04-09 21:04:16